Osteonecrosis of the jaw Infosheet

This Infosheet explains what osteonecrosis of the jaw (ONJ) is and its link to long term bisphosphonate use. It also explains the symptoms of ONJ are and some tips for management.

This Infosheet covers key questions and topics about ONJ, including:

• What is ONJ?
• What are the signs and symptoms of ONJ?
• What is the link between ONJ and myeloma?
• What is the risk that myeloma patients will develop ONJ?
• Risk factors for ONJ
• About bisphosphonates
• Why are bisphosphonates linked to ONJ?
• Management of ONJ
• Treatment of ONJ
• Putting ONJ into perspective
• Self-management tips

Key points you can read about in this Infosheet include:

• ONJ is when one or more parts of the jawbone become exposed inside the mouth
• It may be caused by the use of bisphosphonates to treat myeloma bone disease
• Signs and symptoms of ONJ include areas that will not heal after dental procedures, an area of exposed bone in the mouth, pain or swelling in the gums, loosening of teeth, or a heavy or numb feeling in the jaw
• Self-management tips and good mouth care will help to prevent ONJ
• You should have a dental check-up and any necessary major dental work before starting bisphosphonate treatment. This includes work such as tooth implants and having teeth removed
• If major dental work is unavoidable, it should be carried out by an oral surgeon experienced in ONJ. Your bisphosphonate treatment may be stopped for a time, and restarted once your mouth has healed
• Treatment for ONJ includes the use of antiseptic mouth wash, painkillers, and antibiotics. Sometimes oral surgery is required

Osteonecrosis of the jaw Infosheet

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